Autism is a neuro-developmental disorder that allows a unique window on the relationship between mind and brain. Autism is characterized by impaired social interaction and communication as well as repetitive behaviors and restricted interests. The consensus of this disorder for everyday life adaptation are extremely variable. Studies indicate that the number of diagnosed cases of Autism, or autistic spectrum disorder, is increasing with around 0.6% of the population affected. Though infantile autism was first described almost 60 years ago and autism has been the subject of intense research activities even since, the origin of the condition is still not understood.

Text is derived from a Theme Issue first published by Philosophical Transactions of the Royal Society, Series B. Focuses on new ideas and clinical findings influencing the understanding of autism and its variants. Discusses various therapeutic approaches.