Benchware.Muse v2.1 UU??U??
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?U???UU?? Release Date : 2011-12-29 ??UU???UY
UUUU????? Nfo Date : 2011-12-29 ?????UUUU
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UU? U Num. Disks : xx/48 OS : LINUX,X64 U ?UU
UU? U Nfo Time : 13:37 Rel Type : License U ?UU
UU? U Cracker : Team Lz0 Archive : lz0*.zip U ?UU
UU? U Packer : Team Lz0 Rating : Your choice U ?UU
UU? U Supplier : Team Lz0 Language : English U ?UU
UU? U Protection : FlexLM U ?UU
UU? U U ?UU
UU? U Requirements : N/A U ?UU
UU? U : Always use a firewall. U ?UU
UU? U Publisher URL : http://www.tripos.com U ?UU
UU? U Publisher : Tripos U ?UU
UU? U U ?UU
UU? U (x) Keyfile / License (-) Emulator U ?UU
UU? U (-) Patch (-) Serial U ?UU
UU? U (-) Cracked .EXE / .DLL (-) Retail U ?UU
UU? U (-) Keygen (-) Trainer U ?UU
UU? U U?U (-) Loader (-) Other U?U U ?UU
UU? ?U ? ? U? ?UU
?UU??Y U? U U ?U ???UU?
??UUU?Y ??? UUUUU 1999 - 2011 UUUUU ??? ??UUU??
??U??UU U???? ??U °°° °°° U?? ????U UU??U??
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UUUU????U? U ? ??UUU?U?Y + I N F O + ??UUUUU?? ? U ?U????UUUU
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UU? U? ?U ?UU
UU? U Muse is a molecular design workflow designed to accelerate the U ?UU
UU? U identification and optimization of lead candidates. Using U ?UU
UU? U Muse, CADD Scientists and Medicinal Chemists identify novel U ?UU
UU? U structures, scaffolds, or side-chains that meet specific U ?UU
UU? U design objectives. with Muse, scientists can: U ?UU
UU? U U ?UU
UU? U Explore Lead- and Scaffold-Hopping U ?UU
UU? U U ?UU
UU? U Invent New R-Groups around a fixed scaffold U ?UU
UU? U U ?UU
UU? U Generate ideas that meet multiple design criteria U ?UU
UU? U U ?UU
UU? U Easily integrate in-house or 3rd party scoring methods for use U ?UU
UU? U as design criteria U ?UU
UU? U U ?UU
UU? U Muse uses ligand-based scoring to generate ideas that optimize U ?UU
UU? U the shape and pharmacophoric similarity to a set of lead U ?UU
UU? U structures, and comes with TupletScore, a robust scoring U ?UU
UU? U function, so users can immediately begin invention experiments. U ?UU
UU? U U ?UU
UU? U TupletScore uses flexible templates and is valuable in U ?UU
UU? U situations where the conformation of the lead or active U ?UU
UU? U structures is unknown and also when the binding modes for the U ?UU
UU? U lead compounds is unknown. TupletScore takes into account U ?UU
UU? U Pharmacophore and Unity Tanimoto fingerprint similarity. U ?UU
UU? U U ?UU
UU? U New Scoring Function for Multi-Parameter Optimization U ?UU
UU? U TriposScore is an optional scoring function that can be used U ?UU
UU? U with Muse for ligand based multi-critera drug design. U ?UU
UU? U Developed in collaboration with AstraZeneca, TriposScore has U ?UU
UU? U been extensively validated in drug discovery projects. U ?UU
UU? U TriposScore uses a rigid 3D template and takes into account U ?UU
UU? U shape and pharmacophore similarity but also includes many more U ?UU
UU? U design criteria (E.g. cLogP, MW, TPSA, Lupinski Counts, U ?UU
UU? U Rotatable Bond Counts, ect?). U ?UU
UU? U U ?UU
UU? U Like TupletScore, TriposScore allows users to add their own U ?UU
UU? U in-house 3rd party properties to the workflow. U ?UU
UU? U U ?UU
UU? U Muse and TriposScore can be easily integrated with ANY scoring U ?UU
UU? U function, allowing the user to tailor experiments based on U ?UU
UU? U additional information he already has (E.g. Surflex-Dock, U ?UU
UU? U Topomer CoMFA or Topomer Search from Tripos, or computational U ?UU
UU? U chemistry programs from 3rd party vendors). U ?UU
UU? U U ?UU
UU? ?U ? ? U? ?UU
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U?? ?Y U ???????UU UUUUU???? U ?? ??U
UU? U? ?U ?UU
UU? U 1) Unpack and install. U ?UU
UU? U 2) See install.txt. U ?UU
UU? U 3) Enjoy this release! U ?UU
UU? U U ?UU
UU? U NOTE: For obvious reasons you should always make sure that U ?UU
UU? U the title is restricted access to internet by a firewall U ?UU
UU? U to avoid any problems. Further, when running our U ?UU
UU? U keygens/patches you might need to run it with admin U ?UU
UU? U rights while in Vista/Win7 to ensure that it has U ?UU
UU? U enough privileges. U ?UU
UU? U U ?UU
UU? ?U ? ? U? ?UU
?UU??Y U ? ? U ???UU?
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U?? ?Y U ???????UU UUUUU???? U ?? ??U
UU? U? ?U ?UU
UU? U So you are interested in joining one of the most successful U ?UU
UU? U groups of all time? Then you might want to continue reading. U ?UU
UU? U Not only can we offer whatever your heart might desire, but U ?UU
UU? U becoming part of the group will also be one of the more U ?UU
UU? U significant decisions you perhaps will take. U ?UU
UU? U U ?UU
UU? U Ever since our beginning in 1999 we’ve strived to make a group U ?UU
UU? U that not only is a group of knowledge, but a gathering of U ?UU
UU? U people that wants friendship, devotion, respect and fun. Hard U ?UU
UU? U work is what has brought us where we are today, and hard work U ?UU
UU? U is also what we would expect from you. U ?UU
UU? U U ?UU
UU? U Given the amount of hours we all put into this every day, we U ?UU
UU? U like to see our self as a secondary family. We strive to take U ?UU
UU? U care of each other and thus – mutual respect is the essence of U ?UU
UU? U our group. We never pushed for being elite, as we do not believe U ?UU
UU? U that any of us deserve the mark of the elitists. Every member U ?UU
UU? U of our group is taught to honor the next guy or gal with the U ?UU
UU? U same respect as he or her demands for themselves. The same U ?UU
UU? U thought applies to how we look at other groups. U ?UU
UU? U U ?UU
UU? U Are you ready to become part of a family? Do you think you have U ?UU
UU? U what it takes? Then now is the time to get up and contact us. U ?UU
UU? U Perhaps you will find a new road to follow with us. Open U ?UU
UU? U positions are as follows, but if you do feel you have something U ?UU
UU? U to contribute with but feel that it doesn’t match any of the U ?UU
UU? U open positions, then do contact us and let us be the judge U ?UU
UU? U of that. U ?UU
UU? U U ?UU
UU? U CRACKERS U ?UU
UU? U Do you have a thrill to find solutions to various protection U ?UU
UU? U schemes? May it be unpacking, patching, finding algorithms U ?UU
UU? U or emulating? We’re always open for individuals that want to U ?UU
UU? U expand their knowledge in reversing. You are required to have U ?UU
UU? U some former knowledge in reversing as we do not tutor people U ?UU
UU? U from scratch. Former experience from other scene groups is U ?UU
UU? U good, but not a necessity. Unsure if you qualify? Contact us, U ?UU
UU? U and we’ll decide based on your qualities. Be prepared that U ?UU
UU? U we will demand examples of previous work. U ?UU
UU? U U ?UU
UU? U CODERS U ?UU
UU? U You’re enthusiastic about coding, you love to optimize and U ?UU
UU? U integrate various projects; we always have projects ranging U ?UU
UU? U from smaller ones to large ones that are in need of attendance. U ?UU
UU? U If you are joining our family as a coder you will be appointed U ?UU
UU? U a variety of projects that will push you to do your best and U ?UU
UU? U will probably also serve as a great way of becoming an even U ?UU
UU? U greater coder. Projects are ranging from database integrations, U ?UU
UU? U IRC bots, and cracktros to tools and security oriented U ?UU
UU? U development. Examples of previous work will be required and U ?UU
UU? U experience beyond 2 years is also a requirement. U ?UU
UU? U U ?UU
UU? U SUPPLIERS U ?UU
UU? U Do you have access to good titles? Perhaps you work as an U ?UU
UU? U engineer, network administrator, or by any other means can U ?UU
UU? U acquire the latest versions of what you have access to? Then U ?UU
UU? U feel free to contact us and let us know what you have. We do U ?UU
UU? U not focus on anything in particular and as such you will find U ?UU
UU? U that we do titles ranging from CAD/CAM to more common graphics, U ?UU
UU? U music and programming titles – as well as ordinary shareware U ?UU
UU? U titles. Contact us today and we will see if your titles are U ?UU
UU? U something we’d like to put some effort into. U ?UU
UU? U U ?UU
UU? U SITES U ?UU
UU? U You’ve been running a dedicated and well supported site for U ?UU
UU? U more than 6 months, the site has grown some reputation and your U ?UU
UU? U staff as well as the chosen link location is security oriented. U ?UU
UU? U We do not accept sites that are running of rented boxes; U ?UU
UU? U neither do we accept sites located in United States of America, U ?UU
UU? U Germany or Austria. The speed of the site does not matter, what U ?UU
UU? U do matter is that it’s stable, it’s secure and above all – the U ?UU
UU? U entire site as well as crew is operating encrypted. You feel U ?UU
UU? U that this might be you? Then let us know today, and we will U ?UU
UU? U be getting back to you shortly. U ?UU
UU? U U ?UU
UU? U BOX OPERATORS U ?UU
UU? U You have been running hosting services for years; either being U ?UU
UU? U BNC solutions or IRC daemons – or perhaps just have some boxes U ?UU
UU? U that you might think we can use. You’re an administrator of a U ?UU
UU? U network and have complete control over the box, the network U ?UU
UU? U area and access levels. If so, then you are someone we are U ?UU
UU? U interested to talk to. Keep in mind that we do not offer any U ?UU
UU? U boxes residing in the same countries as mentioned under “SITES”. U ?UU
UU? U U ?UU
UU? U Remember, we all started out somewhere so do not keep yourself U ?UU
UU? U from contacting us thinking you aren’t good enough to help out, U ?UU
UU? U let us decide that. U ?UU
UU? U U ?UU
UU? ?U ? ? U? ?UU
?UU??Y U ? ? U ???UU?
??UUUUY U??U UUUUU UUUUU U??U ?UUUU??
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UUUU????U? U ? ??UUU?U?Y + L E G A L + ??UUUUU?? ? U ?U????UUUU
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UU? U? ?U ?UU
UU? U Our releases are made to make sure that the end-user is able U ?UU
UU? U to fully test a title before going into a purchase as well as U ?UU
UU? U give the end-user an opportunity to make backup copies of U ?UU
UU? U titles he or she already owns. Please do respect our stance U ?UU
UU? U on this and make sure that you buy the required licenses upon U ?UU
UU? U deciding to buy the product. Respect the software authors U ?UU
UU? U that have put time, money and effort into creating the title U ?UU
UU? U you now have in your hand. U ?UU
UU? U U ?UU
UU? U 1. You should only use this title for the period of time U ?UU
UU? U as you decide if this is the right product for you U ?UU
UU? U personally or for your business. Upon deciding U ?UU
UU? U that this is the product you are looking for then U ?UU
UU? U we encourage you to buy the necessary licenses. U ?UU
UU? U U ?UU
UU? U 2. If you already own this title then this release can be U ?UU
UU? U used as a substitute to the original disks for backup U ?UU
UU? U and archiving purposes. This is convenient if you U ?UU
UU? U own a large set of various titles that all require U ?UU
UU? U dongles to run and you keep on mixing up the dongles. U ?UU
UU? U Our releases have removed those checks and thus will U ?UU
UU? U be more convenient to use. Again, this should only U ?UU
UU? U be the case if you own the required licenses. U ?UU
UU? U U ?UU
UU? U 3. We do not wish for our releases to be widely spread U ?UU
UU? U across web boards, P2P networks and the like. While we U ?UU
UU? U do know that occurs we strongly urge people to not U ?UU
UU? U share these titles at such places. U ?UU
UU? U U ?UU
UU? U 4. The group is not involved with the spreading of the U ?UU
UU? U release, partial files or any of the cracks. The U ?UU
UU? U distribution of our releases are all done by third U ?UU
UU? U parties – and as such according to the laws of the U ?UU
UU? U countries where our members reside, it is not our U ?UU
UU? U responsibility what others decides to do with U ?UU
UU? U these releases. U ?UU
UU? U U ?UU
UU? U 5. You are NOT allowed to distribute our titles with the U ?UU
UU? U intent of earning money. This title is not yours to U ?UU
UU? U sell. We, as a group, do not participate in such U ?UU
UU? U actions and we plead to those that are thinking about U ?UU
UU? U selling pirated titles, reconsider – not only are you U ?UU
UU? U hurting us seeing our releases being abused, but above U ?UU
UU? U all – you are actually stealing profit from the U ?UU
UU? U software authors. U ?UU
UU? U U ?UU
UU? U 6. We do not take any responsibility of computer or data U ?UU
UU? U loss that may occur from using our releases. Keep in U ?UU
UU? U mind that you are using a third party solution that U ?UU
UU? U does not come from the original software authors. U ?UU
UU? U However we strive to make perfect releases so the U ?UU
UU? U chances of something like that happening are slim. U ?UU
UU? U U ?UU
UU? U 7. The usage of our cracks is legal in most countries U ?UU
UU? U outside of the United States, if and only if you own a U ?UU
UU? U complete copy of the program or game. But you are U ?UU
UU? U required to read the end user license agreements (EULAs) U ?UU
UU? U that comes with the various titles to be sure that you U ?UU
UU? U are not violating any agreements. U ?UU
UU? U U ?UU
UU? U According to the DMCA ACT in the United States you have no U ?UU
UU? U rights to circumvent any copy protection. Keep this in mind U ?UU
UU? U as the penalties for doing so there are harder than if you U ?UU
UU? U stole the actual title from the self. Our base of operation U ?UU
UU? U however is not located in the states, and thus we are not U ?UU
UU? U bound by any of the legislations like “no electronic theft act” U ?UU
UU? U “digital millennium copyright act” or “the patriot act”. But U ?UU
UU? U you as a end-user might be, so be certain to read the EULAs U ?UU
UU? U that you agree to upon installing something to make sure U ?UU
UU? U you are not breaking any domestic laws. U ?UU
UU? U U ?UU
UU? U Finally, we do encourage you to explore the open source U ?UU
UU? U community. In most cases you will find open and free software U ?UU
UU? U that does exactly what you need, and it won’t cost you U ?UU
UU? U anything. At the same time you can enjoy the feeling of U ?UU
UU? U doing something good, and support the open source community. U ?UU
UU? U U ?UU
UU? U By using this release you agree to the statement written above, U ?UU
UU? U and accept that the responsibility to whet ever the usage of U ?UU
UU? U this title is legal or not is with you and you only. Make sure U ?UU
UU? U that you understand the potential risks of using this release. U ?UU
UU? U U ?UU
UU? ?U ? ? U? ?UU
?UU??Y U ? ? U ???UU?
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UU? U? ?U ?UU
UU? U HERiTAGE, RAZOR1911, F4CG, EMPHASiS, ZENiTH, MYTH U ?UU
UU? U GHOST RiDERS, LEGENDS NEVER DiE, ENFUSiA, BiN U ?UU
UU? U FATiGUED COURiERS NETWORK (FCN) U ?UU
UU? ?U ? CHEMiCAL REACTiON (CRO) ? U? ?UU